Parkinson’s disease rarely occurs in younger individuals. People 60 years and older are at higher risk of PD. The following are the associated risk factors in developing Parkinson’s disease: Researchers are also focusing into alpha-synuclein (a-synuclein) found in the Lewy bodies. The studies about them are still inconclusive, but researchers believe that these substances hold useful information to what causes PD. These are often seen in people with Parkinson’s disease. Lewy bodies are clumps of substances in the brain cells. However, the results are still inconclusive. Exposure to pesticides, herbicides, and industrial pollution is now being looked at as a possible cause of PD. Studies have shown that a minority of cases of PD have genetic involvement. Though the exact cause of Parkinson’s disease is still unknown, there are possible explanations that may be responsible for the condition, such as: The signs and symptoms it present are caused by the loss of nerve cells in the part of the brain called substantia nigra. Parkinson’s disease is an idiopathic illness, which means that its cause is unknown. Their speech may become soft, fast, slur, and their tone may become monotonous. Changes in speech may also be noted in people with PD. Loss of the sense of smell may occur even years before the diagnosis of PD. Unconscious movements such as blinking, smiling, and swinging of hands when walking may be reduced in people with Parkinson’s disease. Most people with PD often have a stooped posture. It may occur in any part of the body and may lead to dystonia or uncontrolled painful muscle cramps. Muscle stiffness is also a common sign of PD. Slowness in movements often make it more difficult for people with PD to complete activities of daily living. Individuals with PD display a distinctive slow and shuffling gait. One other main symptom of PD is slow movements or bradykinesia. It is characterized by the rubbing of thumb and forefinger back and forth. Pill-rolling tremors are common in Parkinson’s disease patients. They are likely to occur when the body is at rest and relaxed. Tremors usually start in the limbs, most commonly in the hands and fingers. The presence of tremors is one of the triad symptoms of Parkinson’s disease. Signs and Symptoms of Parkinson’s Disease
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